ProcreaWinnipeg, Manitoba
Procrea

Hyperstimulation/Intrauterine Insemination (HS/IUI)

HS/IUI represents a two step treatment for infertility. First, hormone therapy is used to improve the ovulatory response. Second, an optimally-prepared semen sample is injected directly into the uterine cavity. In bypassing the vagina and cervix, this treatment is designed to increase both the number of eggs and the number of motile sperm which reach the fallopian tubes. Intrauterine insemination compensates for mild male factor infertility.

Ovarian Stimulation

A number of ovarian follicles begin to develop during each normal menstrual cycle. However, the effect of hormones released by the pituitary gland usually result in the production of only one mature follicle capable of ovulating an egg.

Hyperstimulation therapy involves a daily injection of hormone preparations which increases the number of ovarian follicles capable of ovulating an egg.

Monitoring

During hyperstimulation cycles, it is necessary to monitor the rate of ovarian follicular development to minimize the risk of excessive stimulation and multiple pregnancy. Monitoring involves ultrasound and blood testing. When monitoring indicates that an appropriate number of follicles have developed sufficiently, final maturation is initiated by hormone injection.

Candidates

HS/IUI is used in patients with unexplained infertility and in situations where mild male factor infertility (slightly low sperm count or slightly low sperm motility) exists.

Note:

  • The success of HS/IUI varies widely depending on the cause of infertility. In certain ovulatory disorders and male factor conditions, the rate of conception may approach 25%, similar to that of fertile couples.
  • Multiple pregnancy occurs in approximately one in every four pregnancies.
  • Fallopian tubes must be intact and unobstructed.

     



« HS/IUI is used in patients with unexplained infertility and in situations where mild male factor infertility exists. »